Doctors have described the trial results as 'disappointing'.
A pill containing two HIV drugs that was touted as a potential treatment for the novel coronavirus was not effective, according to a study released late on Wednesday in theA test in Chinese patients with severe Covid-19 disease found the 99 who received AbbVie Inc’s Kaletra, a combination of lopinavir and ritonavir, fared no better than the 100 who received standard care.
People on the drugs showed clinical improvement after a median of 15 days compared to 16 days with standard care, a difference the researchers characterised as “significant, albeit modest.”The lopinavir-ritonavir combination also produced more side effects, prompting the treatments to be halted in 13.8% of patients.
The treatment “was not associated with clinical improvement or mortality in seriously ill patients with Covid-19 different from that associated with standard care alone,” concluded the team, led by Dr. Bin Cao of the National Clinical Research Center for Respiratory Diseases.
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