I am a scientist, businessman, author, and philanthropist. For nearly two decades, I was a professor at Harvard Medical School and Harvard School of Public Health where I founded two academic research departments, the Division of Biochemical Pharmacology and the Division of Human Retrovirology.
Muscles keep us moving — they are the engine of the body. But as we age, we naturally begin to lose muscle mass , and with it, strength. Slowing this process down is key to a healthy and long life. A, which is produced by muscle cells and helps stimulate both repair and growth. We may be able to harness the protein to develop therapies for muscular injuries and age-related muscle loss. Myokines are small proteins produced by muscle cells, usually during exercise.
Given the importance of myotubes to muscle contraction and strength, the researchers checked to see if exposing them to platelet-derived growth factor subunit B had any impact. Surprisingly, adding the protein to myotubes resulted in a significant increase in their diameter, as visible under a microscope.
Testing the treated myotubes for contractile force proved that the changes were not only cosmetic: they noticeably outperformed their untreated counterparts. This suggests that platelet-derived growth factor subunit B not only helps boost muscle formation, it also helps boost muscle strength.Age-related muscle loss is a serious threat to well-being, both physical and emotional. It can cause a drop in quality of life, and once it sets in, it can be difficult to reverse.
Myokines like platelet-derived growth factor subunit B may help provide new treatment options that replicate the benefits of regular exercise. This would be a game-changer for many older adults who, due to mobility issues, struggle to work out. Harnessing such proteins could allow us to artificially stimulate muscle growth and strength, curbing the usual muscular problems associated with aging.
Health Aging Longevity Muscles Muscle Mass Exercise Fitness Proteins Myokines
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