A secondary analysis of four randomized trials showed that a single MDMA dose resulted in a 31% incidence of acute hyponatremia, but this could be prevented by restricting fluid intake.
The high incidence of acute hyponatremia after the administration of a single dose of 3,4-methylenedioxymethamphetamine , also known as ecstasy, in healthy individuals may be mediated by oxytocin rather than vasopressin and can be reduced with fluid restriction.MDMA is being studied as a potential treatment for posttraumatic stress disorder ; however, even a single dose of this medication can cause acute hyponatremia, a condition characterized by low levels of sodium in the blood.
Measurements were taken of plasma oxytocin, copeptin, and sodium levels repeatedly within 360 minutes after MDMA intake, with the peak MDMA concentration expected at 180 minutes. Hyponatremia occurred in 31% of participants, with the decrease in plasma sodium levels at 180 minutes after MDMA administration more pronounced in those receiving higher doses (Fluid restriction demonstrated significant protective effects, as none of the participants in the fluid-restricted group experienced hyponatremia, in contrast to 37% of those in the fluid-unrestricted group (
Hyponatraemia Plasma Oxytocin Pregnancy Pregnant Grant Stress Healthcare And Medical Technology Health And Medical Tech Health And Med Tech Health And Medical Technology Healthcare Technology Medical Technology PTSD PTSD - Post Traumatic Stress Disorder Post Traumatic Stress Disorder Post Traumatic Stress Syndrome Posttraumatic Stress Disorder Artificial Intelligence
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Hospitals’ IV fluid shortage may affect surgeries for weeksSurgery schedules may be affected for weeks after an IV and sterile fluids factory shut down after a hurricane. Texas Medical Association urges conservation.
Read more »
IV Fluid Shortage May Change Hospital Hydration PracticesHospitals around the country are conserving critical intravenous fluid supplies to cope with a shortage that may last months.
Read more »
Psychedelics Like Psilocybin, MDMA Tied to Higher Odds for SchizophreniaPeople are at higher risk of schizophrenia if they indulge in psychedelic drugs, a new study warns.
Read more »
Man facing charges after receiving cocaine, ketamine, MDMA through US Postal ServiceA man is facing several charges after he allegedly received various drugs via the U.S. Postal Service.Elijah Sky Carrillo, 43, was arrested Thursday on one thir
Read more »
How Bay Area hospitals are responding to national IV fluid shortageHealth care facilities in the Bay Area are changing protocols to account for the national shortage of IV fluids.
Read more »
JJ Redick To Have 'Fluid' Starting Lineup But Won't 'Overreact'JJ Redick To Have Fluid Starting Lineup But Wont Overreact - RealGM Wiretap
Read more »