FDG-PET/CT imaging performed 3 months after chemoradiation for head and neck squamous cell carcinoma spares many patients from a salvage neck dissection, new data indicate.
For patients with head and neck squamous cell carcinoma , utilizing fluorodeoxyglucose--PET/CT imaging to assess their response to chemoradiation significantly increases the accuracy in identifying which patients would benefit from salvage neck dissection , ultimately reducing the number of patients who undergo unnecessary surgery.
The primary endpoint was the positive predictive value of FDG-PET/CT for pathologic-confirmed residual disease after salvage neck dissection compared with MRI, CT, or ultrasound with fine needle aspiration. Secondary endpoints were oncologic outcomes. FDG-PET/CT had significantly better positive predictive value for detecting pathologic-confirmed residual disease compared with MRI/CT plus ultrasound . FDG-PET/CT significantly improved the accuracy of the detection of pathologic-confirmed residual disease, thereby reducing the number of patients undergoing unnecessary salvage neck dissection by 22%.
Head And Neck Cancer Head And Neck Cancer (HNC) Otolaryngology ENT Specialty Head And Neck Surgery ENT Speciality Neck Dissection Neck Cervical Region Of Neck Squamous Carcinoma Squamous Cancer Squamous Cell Carcinoma Cancer Malignant Neoplasia Carcinoma Malignant Neoplasm Residual Disease Surgery Ultrasonography Ultrasound Sonogram Aspiration
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