FDA chief's long-promised opioid review faces skepticism

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FDA chief's long-promised opioid review faces skepticism
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The head of the Food and Drug Administration says a comprehensive review of the opioid painkillers that triggered the nation's ongoing overdose epidemic is in the works

FILE - U.S. Food and Drug Administration Commissioner Dr. Robert Califf speaks at a news conference at the Hubert H. Humphrey Building in Washington, Thursday, May 5, 2016. Califf says a comprehensive review of the opioid painkillers that triggered the nation's ongoing drug overdose epidemic is in the works. But he faces skepticism about the long-promised review from lawmakers, experts and advocates after years of delay. WASHINGTON — — As U.S.

Bonnie and his co-authors say the FDA seems to have incorporated several of their recommendations into recent decisions, including a broader consideration of a drug’s public health risks. But they say there is more to be done. At the center of the recommendations was a proposal for the FDA to reassess the dozens of opioids being sold to determine whether their overall benefits in treating pain outweigh their risks of addiction and overdose. Those that don’t should be removed from the market, the group said.

Opioid prescriptions have fallen about 40% in the last decade amid restrictions by hospitals, insurers and state officials. But deaths tied to the medications remain at 13,000 to 14,000 per year. And studies suggest people who become addicted to opioids continue to start with prescription opioids, before switching to cheaper heroin and illegally made fentanyl.

“I think what you’ve seen is the agency grabbing at some of the low-hanging fruit and only to a certain level,” Riley said.

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