FDA approves 1st RSV vaccine for use in pregnancy to stop infection in newborns

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FDA approves 1st RSV vaccine for use in pregnancy to stop infection in newborns
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The FDA just approved an RSV vaccine that can be given in the third trimester of pregnancy.

A respiratory syncytial virus vaccine has just been approved for use in pregnant people that protects against dangerous infection in newborns.

The vaccine prompts the pregnant person's immune system to make protective antibodies that then pass to the fetus through the placenta. In addition, as with other vaccines given in pregnancy, the antibodies may also pass to newborns through normal breast milk and the nutrient-dense colostrum made just after birth.

In most people, RSV causes mild, cold-like illnesses that resolve without medical attention. But infants, young children and people older than 65 can develop severe disease and potentially die from the virus. In a clinical trial, 3,500 pregnant people received Abrysvo and another 3,500 received a placebo injection. In the 90 days after birth, the vaccinated group's babies had a 81.8% lower chance of severe lower respiratory tract disease — meaning severe lung infections — from RSV than the unvaccinated group's babies. And 180 days after birth, the vaccinated group's rate of severe infection was still 69.4% lower.

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FDA approves 1st maternal RSV vaccine to help protect infantsThe U.S. Food and Drug Administration has approved the first maternal vaccine intended to help protect newborns against respiratory syncytial virus (RSV).
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