A new mouse study published in the journal suggests that the female hormone estrogen could be a key factor in binge drinking behavior among women. Researchers found that female mice with higher estrogen levels consumed more alcohol, particularly within the first 30 minutes of availability. This binge drinking was linked to increased activity in the bed nucleus of the stria terminalis (BNST), a brain region associated with drinking behavior. The study also revealed that estrogen directly excites neurons in this region, providing a rapid mechanism for influencing behavior.
The female hormone estrogen appears to promote binge drinking in women, a new mouse study published recently in the journalThis study provides what could be the first explanation for sex-related differences in binge drinking , said senior researcher Kristen Pleil, an assistant professor of pharmacology with Weill Cornell Medicine.
Further, this binge drinking was linked to heightened activity in a brain region called the bed nucleus of the stria terminalis , which had been previously linked to drinking behavior, researchers added. The team also noted that estrogen directly excites these neurons -- a surprising revelation, given that the hormone typically influences behavior through an hours-long process of altering gene activity rather than targeting brain cells.
Binge Drinking Estrogen Women's Health Neurobiology Alcohol Consumption
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