A new study suggests that ultra-processed foods and inflammatory seed oils used in packaged food products may contribute to chronic inflammation, fueling colorectal cancer.
Its findings pave the way for a new therapy -- resolution medicine -- which uses natural products in lieu of synthetic drugs to help reverse inflammation and potentially reverse colorectal cancer.
According to Yeatman, the findings emphasize the urgent need to reevaluate the components of the Western diet, which typically consists of excessive consumption of added sugars, saturated fats, ultra-processed foods, chemicals and inflammatory seed oils. In previous studies, the USF Health Heart Institute found an imbalanced diet not only impacts colorectal cancer, but also plays a role in other diseases, including Alzheimer's, diabetes and cardiovascular conditions.
Inside the tumors, the team observed an excess number of molecules that promote inflammation and a shortage of those that help resolve it and promote healing. These findings pave the way for a new, natural approach -- resolution medicine -- which focuses on restoring balance in the patient's diet to treat colorectal cancer more effectively.
"This has the potential to revolutionize cancer treatment, moving beyond drugs to harness natural healing processes," Yeatman said."It's a vital step toward addressing chronic inflammation and preventing diseases before they start."
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