A study involving 22 Parkinson's disease (PD) patients has shown that use of the dopaminergic drug levodopa improves sleep quality.
São Paulo Research Foundation Aug 13 2024 A study involving 22 Parkinson's disease patients has shown that use of the dopaminergic drug levodopa improves sleep quality. When the patients took the drug, the number of times they woke up during the night fell 25% and the amount of time they remained awake fell 30% on average.
This was the first study to evaluate the effects of the drug on sleep quality in PD patients objectively and to compare them with the results reported subjectively. The actigraphic readings pointed to an improvement in sleep quality after the patients took the drug, although they themselves didn't experience any benefit. This is important from the standpoint of clinical care.
Although dopaminergic medication may also improve sleep quality by reducing sleep onset latency and wakefulness in PD patients, there are documented reports of potential sleep disturbance exacerbation resulting from treatment with levodopa. It bears recalling that the drug should be used only when prescribed by a physician. Possible side effects include confusion, drowsiness, insomnia, nightmares, hallucinations, delusion, agitation, anxiety and euphoria.
Sleep and mobility Impairment of sleep quality is also associated with freezing of gait – a sudden inability to initiate or continue movement, often resulting in a fall, and one of the most incapacitating symptoms of PD.
Sleep Drowsiness Education Insomnia Levodopa Parkinson's Disease Research
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Study finds that dopaminergic medication improves sleep quality in Parkinson's disease patientsA study involving 22 Parkinson's disease (PD) patients has shown that use of the dopaminergic drug levodopa improves sleep quality. When the patients took the drug, the number of times they woke up during the night fell 25% and the amount of time they remained awake fell 30% on average.
Read more »
New insights into lipid-induced senescence in dopaminergic neuronsA new research perspective was published in Aging (listed by MEDLINE/PubMed as 'Aging (Albany NY)' and 'Aging-US' by Web of Science), Volume 16, Issue 14 on July 19, 2024, entitled, 'Lipid accumulation drives cellular senescence in dopaminergic neurons.
Read more »
New insights into lipid-induced senescence in dopaminergic neuronsA new research perspective was published in Aging (listed by MEDLINE/PubMed as 'Aging (Albany NY)' and 'Aging-US' by Web of Science), Volume 16, Issue 14 on July 19, 2024, entitled, 'Lipid accumulation drives cellular senescence in dopaminergic neurons.
Read more »
Lipid accumulation drives cellular senescence in dopaminergic neuronsA new research perspective titled Lipid accumulation drives cellular senescence in dopaminergic neurons has been published in Aging.
Read more »
Blood test may aid early detection of Parkinson's and guide treatment strategiesTo date Parkinson's disease (PD) is diagnosed clinically and rather late in the course of the disease. There is an urgent need to find an objective, quantifiable biomarker for the diagnosis of this highly prevalent movement disorder.
Read more »
New preclinical model offers a unique platform for studying Parkinson's disease processA new preclinical model offers a unique platform for studying the Parkinson's disease process and suggests a relatively easy method for detecting the disease in people, according to a new study led by Weill Cornell Medicine researchers.
Read more »