In univariate analysis, vitamin D deficiency was associated with younger age, Black race, female sex, and higher obstructive Apnea-Hypopnea Index.
and is associated with increased OSA severity. Lower serum 25-hydroxyvitamin D levels correlate with higher obstructive Apnea-Hypopnea Index scores.Researchers conducted a cross-sectional study involving 72 children aged 2-16 years with severe OSA undergoing adenotonsillectomy.
Participants were recruited from a tertiary care pediatric otolaryngology clinic in Norfolk, Virginia, over a 5-year period from 2017 to 2022.Data were analyzed from September 3, 2021, to October 8, 2021, using a generalized linear model and multivariable linear regression.In a univariate analysis, vitamin D deficiency was associated with younger age, Black race, female sex, and higher obstructive AHI .
“One potential association between vitamin D status and OSA involves the role that vitamin D plays in immunomodulation and tissue growth. Vitamin D has been shown to play an anti-inflammatory role in its modulation of cytokine production and has additionally been reported to affect differentiation of macrophages and monocytes. Low vitamin D levels may increase the risk for OSA by promoting adenotonsillar hypertrophy and chronic rhinitis,” the authors of the study wrote.
This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.
Sleep Apnoea Otolaryngology ENT Specialty Head And Neck Surgery ENT Speciality Sleep Disturbance Abnormal Sleep Pattern Sleep Disorder Somnipathy Vitamin D Deficiency Vitamins Children Child Childhood Pediatrics Kids Obstructive Sleep Apnea Obstructive Sleep Apnea Syndrome Obstructive Sleep Apnoea Obstructive Sleep Apnoea Syndrome Sleep Virginia
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