The Centers for Disease Control and Prevention (CDC) says that smallpox and monkeypox are so closely related that the smallpox vaccine is effective against both diseases
suggests that the smallpox vaccine has been 85% effective against the monkeypox virus. You can receive the smallpox vaccine after being exposed to monkeypox, although the CDC advises that the sooner you get vaccinated after exposure the better.
If you have been exposed to monkeypox and have not received the smallpox vaccine within the past three years, the CDC also advises that you get vaccinated.
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