Does Intensive Follow-Up Testing Improve Survival in CRC?

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Does Intensive Follow-Up Testing Improve Survival in CRC?
Colorectal Cancer (CRC)CancerMalignant Neoplasia
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Intensive follow-up testing in patients with stage II or III CRC following curative surgery does not appear to improve 10-year overall or colorectal cancer–specific mortality rates.

In patients with stage II or III colorectal cancer , frequent follow-up testing with CT scans and serum carcinoembryonic antigen screening provides no significant overall or cancer-specific survival benefits at 10 years, according to findings from a secondary analysis.After curative surgery for CRC, intensive patient follow-up is common in clinical practice. However, there’s limited evidence to suggest that more frequent testing provides a long-term survival benefit.

This secondary analysis of the COLOFOL trial included 2456 patients , 1227 of whom received high-frequency follow-up and 1229 of whom received low-frequency follow-up.

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