Microbial biomarkers for type 1 diabetes may be present in infants as young as 12 months old, suggesting the potential to mitigate disease onset by nurturing a healthy gut microbiome early, show data from the Swedish general population. medtwitter
, alongside Patricia L. Milletich, PhD candidate, from the University of Florida, Gainesville.
Currently, beta-cell autoantibodies are used to predict disease, which are usually only identifiable between 9 and 36 months of age. "While the effective number of cases was very small [n=16], the results were apparently adjusted for multiple comparisons, and significant differences were noted in the microbiome of cases versus controls at 1 year of age. This was 12 years prior to the average age of type 1 diabetes diagnosis in the cases," he said.
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