Clinical trials assess a precision-medicine approach to cancer screening. News feature from sofiamoutinhoBR, part of our focus on Building Healthy Populations.
in treating men at low or intermediate risk of prostate cancer detected by screening with PSA.
The ProScreen trial also includes a flexible screening interval whereby men with low PSA levels get a second test 6 years later, compared with 4 years for those with intermediate PSA levels and 2 years for those with high levels. The researchers hope to reduce over-detection and unnecessary biopsies by 50%.
A more personalized approach to cervical cancer is also gaining ground. In 2020, the American Society for Colposcopy and Cervical Pathology recommended for the first time that doctors estimate a patient’s individual risk of developing pre-cancer or cancer on the basis of the combination of their current and past Pap, HPV and cervical biopsy results, rather than age.
Several randomized trials of FIT versus colonoscopy for colorectal-cancer screening are ongoing, but the European Commission has already recommended FIT as the
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