NRG Oncology NRG-GY018 study demonstrates significantly improved progression free survival outcomes for women with advanced or recurrent endometrial cancer with the addition of pembrolizumab to chemotherapy. NRG Oncology Phase III clinical trial, NRG-GY018, evaluating pembrolizumab in combination
Endometrial cancer is a type of cancer that starts in the lining of the uterus, called the endometrium. It is the most common type of uterine cancer. Symptoms can include abnormal vaginal bleeding, pelvic pain, and weight loss. The exact cause of endometrial cancer is not known, but certain factors such as obesity, hormonal imbalances, and a family history of cancer may increase the risk. Treatment options for endometrial cancer may include surgery, radiation therapy, and chemotherapy.
NRG Oncology Phase III clinical trial, NRG-GY018, evaluating pembrolizumab in combination with standard of care chemotherapy met its primary endpoint of progression free survival for the treatment of patients with stage III-IV or recurrent endometrial carcinoma, regardless of mismatch repair status.
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