The FDA has approved clinical trials for gene-edited pig kidney transplants in humans, marking a major step in tackling the US organ shortage.
In a significant development for organ transplantation, two U.S. biotechnology companies, United Therapeutics and eGenesis, have received clearance from the Food and Drug Administration to proceed with clinical trials involving gene-edited pig kidneys intended for human use.This milestone comes amidst an ongoing organ shortage in the United States, where more than 100,000 individuals are currently awaiting transplants, over 90,000 of which are for kidney replacements.
Xenotransplantation, the process of transplanting organs from one species to another, has long been a goal in medical science, yet it has presented numerous challenges.Early attempts involving primates faced significant hurdles, but advancements in gene editing and immune system management have reignited interest.
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