Belly fat linked to signs of Alzheimer’s 20 years before symptoms begin, study says

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Belly fat linked to signs of Alzheimer’s 20 years before symptoms begin, study says
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Belly fat, also known as visceral fat, may contribute to brain atrophy and early markers of Alzheimer’s disease, new research found.

As the size of a person’s belly grows, the memory center of their brain shrinks and beta amyloid and tau may appear — all of this occurring as early as a person’s 40s and 50s, well before any cognitive decline is apparent, according to new research. Both beta amyloid plaques and tau tangles are early signs of the brain’s march toward a possible Alzheimer’s disease diagnosis. Amyloid plaques typically appear first, with tau tangles arriving later as the disease progresses.

“The more visceral fat one has, the more inflammation happens in the body and it’s much worse, in truth, than the inflammation that occurs with subcutaneous fat,” Raji said. Visceral fat receives more blood flow due to its placement near organs and is more hormonally active than subcutaneous fat, Raji said.

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