Alcohol-mediated renal denervation significantly reduced 24-hour ambulatory systolic blood pressure in uncontrolled hypertension, the sham-controlled TARGET BP I trial showed.
"We saw a modest but statistically significant difference in the primary endpoint, but there were no significant differences in other measures of blood pressure, including office systolic or diastolic blood pressure," said lead author David E. Kandzari, MD, chief of the Piedmont Heart Institute and cardiovascular service line, director of interventional cardiology at Piedmont Heart Institute, and chief scientific officer for Piedmont Health Care, Atlanta.
Baseline mean 24-hour SBP/diastolic BP was 146.3/87.2 mmHg for the RDN group and 146.2/87.6 mmHg for the sham control group, with a corresponding mean office BP of 164.3/98.4 mmHg and 163.9/100.0 mmHg for the RDN and sham control groups, respectively. The primary efficacy endpoint was change in mean 24-hour ambulatory SBP from baseline to 3 months post procedure.
However, compliance was an issue even among patients who should be more be compliant as they're getting more follow-up, said Rymer."You can certainly imagine if there are these types of compliance issues within a clinical trial setting what it would be like in real world practice.", Samin K.
Myocardial Infarction Blood Adherence Adherence To Medication Issues For Patients Compliance Drug Compliance Treatment Adherence Arteries Renal Denervation Renal Artery Stenosis Stenosis Of The Renal Artery Cardiac Surgeries Cardiac Surgery Uncontrolled Hypertension Cardiomyopathy Cardiovascular Imaging Cardiac Imaging CV Imaging Antihypertensive Heart Hypotension Stenosis
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Increase in Alcohol-Related Deaths and Alcohol Consumption During the PandemicA new report reveals a rise in alcohol-related deaths in the U.S., with 178,307 deaths between 2020 and 2021. Alcohol sales also increased significantly in 2020. Mothers with young children saw a substantial increase in alcohol consumption during the pandemic. Additionally, suicide deaths reached a record high in 2022.
Read more »
Study Reveals Glucagon Receptors' Role in Renal HealthIn findings with implications for future therapies in chronic kidney disease, mouse studies show a protective effect of glucagon receptor signaling in the kidney.
Read more »
Why Are Alcohol-Related Deaths Skyrocketing Among Women?Women fare worse drinking less over a shorter period of time.
Read more »
Luxury Alcohol Brands Hone in on Lifestyle MarketingFrom Martell to The Macallan, LUXUO looks at how alcohol brands shift toward the lifestyle sector to market to broader consumers.
Read more »
Gov. Inslee signs 'Strippers' Bill of Rights' into law, paving way for alcohol salesNew rules are coming to strip clubs that could make work conditions safer for dancers and eventually allow alcohol sales at these businesses.
Read more »
‘Strippers Bill of Rights’ signed into law, allows adult establishments to serve alcoholThe Washington state House advanced a so-called ‘Strippers Bill of Rights’ along a party-line vote 58-36, but not before making substantial changes to the original Senate version.
Read more »