A Less Invasive Route to Being Seizure-Free: Stereotactic Laser Ablation

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A Less Invasive Route to Being Seizure-Free: Stereotactic Laser Ablation
Seizure DisorderLaserLaser Therapy
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Drs Andrew Wilner and Robert Gross discuss a minimally invasive approach to treating mesial temporal lobe epilepsy and how its efficacy compares with surgery.

Associate Professor of Neurology, University of Tennessee Health Science Center, Memphis, TennesseeServe as a director, officer, partner, employee, advisor, consultant, or trustee for: Accordant Health Services, a CVS Caremark Co.

Through that catheter, we can pass a fiber optic down into the brain and heat the brain up to the temperature at which it essentially melts in a very discreet area, and guide that with the MRI scan, which actually can show us the heating of the brain so that we can be sure that we're ablating — and that's the word we use for this — exactly the area we need to ablate, no more and no less.

Based on our data and others’ data, we suspected that it wasn't quite as successful as doing, let's call it the maximal surgery, or an anterior temporal lobectomy. We figured it was safer because there were fewer complications. It sounds like this laser ablation technique is taking out as little as possible to preserve brain function and also make it a lot easier on the patient in terms of side effects, back-to-work time, and comfort.Yes, what you said is true. If we do a hemispherotomy or a hemispherectomy and remove the whole hemisphere, which we do in certain instances when it's a very widespread pathology, that would be the most effective thing to do.

It is still a technique that is used in a number of people's hands I can think of, in particular in Marseilles, France, but it never was able to take off after that failed randomized clinical trial here in the United States.

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