Novel ways of administering opioid analgesics improve pain management and satisfaction in cancer patients.
in managing severe cancer pain , according to new research presented here at the European Society for Medical Oncology Congress.guidelines recommend maintaining analgesia for persistent cancer pain with conventional oral extended-release morphine around the clock as a background dose, supplemented with immediate-release morphine as a rescue dose for breakthrough pain .
The multicenter study conducted in 48 research centers in China involved 1364 patients with malignant solid tumors and persistent, severe cancer-related pain . Participants were stratified based on whether they had received opioid analgesics for more than 7 consecutive days in the past 30 days and were divided into three groups, each receiving opioid analgesics through different methods over a 24-hour period.
"Two important WHO pain relief principles are oral administration and administration on time," explained Lin."However, our research shows that for patients with severe cancer pain, the intravenous administration mode may be superior to oral administration, with less morphine consumption, higher patient satisfaction with pain control, and fewer side effects."
Pain Management Pain Cancer Pain Pain From Cancer Cancer-Related Pain Breakthrough Pain Analgesia Analgesic Painkiller Cancer Malignant Neoplasia Carcinoma Malignant Neoplasm Opioids Intravenous IV - Intravenous Intravenous Route Patient Controlled Analgesia Patient Safety Adverse Effects Side Effects Hospitals
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