How psilocybin, the psychedelic in mushrooms, may rewire the brain to ease depression, anxiety and more

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How psilocybin, the psychedelic in mushrooms, may rewire the brain to ease depression, anxiety and more
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Scientists are learning more about how psychedelic mushrooms may alter the brain, potentially leading to long-lasting reversals of depression, anxiety, cluster headaches and more.

Shrooms, Alice, tweezes, mushies, hongos, pizza toppings, magic mushrooms — everyday lingo for psychedelic mushrooms seems to grow with each generation. Yet leading mycologist Paul Stamets believes it’s time for fans of psilocybin mushrooms to leave such childish slang behind. “Let’s be adults about this. These are no longer ‘shrooms.’ These are no longer party drugs for young people,” Stamets told CNN. “Psilocybin mushrooms are nonaddictive, life-changing substances.

’ If people really have changed the way their brain is automatically hardwired to respond to triggers for anxiety, depression, smoking — that’s a real thing.” How long do results last? In studies where patients were given just one dose of a psychedelic “a couple of people were better eight years later, but for the majority of those with chronic depression it creeps back after four or five months,” Nutt said. “What we do with those people is unknown,” he added.

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