Zepbound is Eli Lilly’s new weight loss drug: What to know

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Zepbound is Eli Lilly’s new weight loss drug: What to know
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Berkeley Lovelace Jr. is a health and medical reporter for NBC News. He covers the Food and Drug Administration, with a special focus on Covid vaccines, prescription drug pricing and health care. He previously covered the biotech and pharmaceutical industry with CNBC.

A new weight loss drug has been approved that promises to be the most effective medication yet. How is Zepbound, the weekly injectable drug that’s expected to be available shortly after Thanksgiving, different from other weight loss medications? Zepbound, from drugmaker Eli Lilly, belongs to a new class of medications, called GLP-1 agonists, that have skyrocketed in popularity in the U.S. in recent years. Novo Nordisk's Ozempic and Wegovy and Lilly’s Mounjaro are the same type of drugs.

Wegovy is approved for people 12 and older. On Zepbound’s label, the FDA notes that the safety and effectiveness of Zepbound have not yet been established in teens or adolescents. McGowan stressed that both medications are highly effective. When deciding between Zepbound and Wegovy, he said patients should consider two factors: insurance coverage and their individual response to each treatment.

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