There have been several nods to The Lizard's past.
Summary SCREENRANT VIDEO OF THE DAY SCROLL TO CONTINUE WITH CONTENT Dr. Curt Connors will be appearing in Marvel's Spider-Man 2, and the May 2023 PlayStation Showcase gave players a look at his reptilian alter-ego: The Lizard. Although this was the first time seeing Insomniac Games' iteration of the character, he had already been teased several times throughout the acclaimed superhero series, making his return somewhat inevitable.
Marvel's Spider-Man Referenced Peter Parker & Curt Connors' Past Marvel's Spider-Man: Miles Morales introduced Curt Connors in a post-credits sequence. In this scene, Connors is working with Norman Osborn on the secret symbiote experiment to cure Harry Osborn of a terminal illness, something that will ultimately unleash the fan-favorite Spider-Man foe Venom upon the city.
One Redditor, viperbite25 shared a screenshot of the vial on the SpidermanPS4 subreddit. With it, they pointed out that The Lizard's appearance in the upcoming sequel would be a return in-universe, and theorized that Norman Osborn could be responsible for Connors' regression after being cured. A Halloween Costume Showed The Lizard's Previous Form During Marvel's Spider-Man's main campaign, Peter infiltrates a Halloween party at his former university, Empire State University. In this level, several students and professors can be seen wearing costumes based on the more traditional comic book iteration of Spider-Man's villains, and the person Peter is looking for, Dr.