Unite members are walking out in an ongoing pay dispute with the government.
Yorkshire Ambulance Service has warned of delays in responding to emergency calls as staff strike.
Unite members in April voted to reject ministers' pay offer, which the union said did not address "fundamental problems undermining the NHS".Unite members at YAS will walkout between 14:00 and 22:00 BST as the union looks to pressure the government into reopening negotiations. Nick Smith, executive director at Yorkshire Ambulance Service NHS Trust, said: "It's very important that people use our emergency service appropriately on Friday so that resources can be focused where they are needed, and particularly on very serious and life-threatening incidents."
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