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A team led by researchers from the University of Rennes and Paris-Saclay University in France ran a series of experiments on mice, measuring their reactions to rotating shifts in diet across several weeks.
What's more, there were long-lasting changes in the mice's gut bacteria, changing their internal metabolism. Crucially, when the altered gut bacteria were implanted in mice that hadn't been dieting, they showed the same binge eating behavior. It's as if dieting creates shifts in the gut microbiome that then bring on"We showed that alternation between high-energy and standard diet durably remodels the gut microbiota toward a profile that is associated with an increase in hedonic appetite and weight gain," By carefully analysing the brain patterns of the mice on the dieting schedule, the researchers could see that they were probably eating for pleasure rather than because they were hungry – as if Mice that switched to and from a Western diet were compared with a control group . (Fouesnard et al.,could bring on certain shifts in the mix of bacteria in the gut that make it harder to maintain a healthy diet."Weight maintenance during restrictive yo-yo dieting might be impeded not only by metabolic adaptations but also by modified food reward-related processes,"that can come with it, the hope is that we can improve therapies for tackling obesity and promoting healthy eating – perhaps by targeting particular types of gut bacteria.This also needs to be documented in human trials too, of course. "More work is definitely needed to fully understand the mechanisms at play in this model, especially regarding the gut microbiota to brain transduction pathways involved in this weight cycling-induced altered eating behavior,"
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