XBB/XBB.1.5 subvariant of SARS-CoV-2 shows increased vaccine sensitivity SARSCoV2 Vaccine Coronavirus Disease COVID medrxivpreprint CDCgov KPSCALnews UCBerkeley
By Dr. Sanchari Sinha Dutta, Ph.D.Mar 19 2023Reviewed by Danielle Ellis, B.Sc. *Important notice: medRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as established information.
In the current study, scientists have explored whether omicron subvariant XBB/XBB.1.5 is more sensitive or resistant than omicron BA.5-related subvariants to host immune responses acquired through infection or vaccination. Important observations The study analysis revealed that the cases with XBB/XBB.1.5 Infections have received a lower number of coronavirus disease 2019 vaccine doses compared to the cases infected with other co-circulating subvariants. Moreover, XBB/XBB.1.5-infected cases showed a relatively higher probability of having previous SARS-CoV-2 infections, irrespective of vaccination status.
These observations further highlight the importance of COVID-19 vaccination in preventing XBB/XBB.1.5 infection and disease progression.
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