XBB.1.5: What we know to date on this currently dominant viral subvariant

Here’s what we know – and don’t – about XBB.1.5.

Research suggests that the bivalent Covid-19 vaccines are more effective in producing an antibody response to XBB.1.5, compared to the earlier vaccines. — AFP

The European Centre for Disease Prevention and Control said a week earlier that XBB.1.5 accounted for less than 2.5% of cases in Europe. XBB.1.5 has a growth advantage over other Omicron viral variants of 109% in North America and 113% in Europe, the European Union health agency added, though it cautioned that these figures came with “significant uncertainty”.But Dr Roberts said that “there’s no data to suggest XBB.1.5 is any more harmful in terms of severe disease and death than previous variants”.

Dr Roberts pointed to a recent preprint study, which has not been peer-reviewed, that suggests XBB.1.5 has a similar antibody resistance to XBB.1, but is more transmissible. That is because “the spike protein of the BA.5 bivalent more closely resembles XBB.1.5 than the Wuhan ancestral spike,” he wrote on Substack on Jan 13 .“I don’t think we need to take any drastic action at present,” she said, adding that it remains important for countries to monitor the subvariant’s progress.

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