World’s first immortal lip cells created in a groundbreaking lab study

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World’s first immortal lip cells created in a groundbreaking lab study
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Lip problems, simply, have been impossible to treat. Dr. Martin Egen at Bern University Hospital 'just changed that.'

Researchers from the University of Bern achieve a significant first step in lip research by producing immortalized lip cells in the lab.Researchers at the University of Bern made a big leap in lip research by successfully immortalizing lip cells from healthy and cleft lips.

The lack of available lip cells has hindered the advancement of this much-needed area of research by limiting the ability to create adequate clinical models. Lip problems, simply, have been impossible to treat. Dr. Martin Egen at Bern University Hospital “just changed that,” propelling this field of medicine forward using lip tissue that clinicians normally discard.scientists confirmed that they reached an important initial step “in developing clinically relevant lip models in the lab” which could help thousands of patients.

“Three-dimensional lip models, generated using these cell lines, proved to be effective and convenient platforms for screening applications, including wound healing and microbial infection of the lip epithelium,” the study’s authorsHowever, these 3D models are the first of their kind, opening up a whole new field of possibilities for various fields of medicine “such as dermatology, skin care, wound healing, tissue engineering, and craniofacial anomalies.

“One challenge is that lip keratinocytes can be of labial skin, mucosal, or mixed character,” he added. “Depending on the research question, a particular cell identity might be required. But we have the tools to characterize or purify these individual populations Originally from LA, Maria Mocerino has been published in Business Insider, The Irish Examiner, The Rogue Mag, Chacruna Institute for Psychedelic Plant Medicines, and now Interesting Engineering.

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