In lab tests, the blood stem cells effectively developed into “functional bone marrow” in immune-deficient mice.
The researchers expect to initiate clinical trials within the next five years to assess the safety of the lab-grown blood cells.
Interestingly, these cells can be reprogrammed from any patient’s cells, offering the potential for personalized treatments. Moreover, the lab-grown cells were successfully frozen and thawed without compromising their ability to function as bone marrow. This ability to freeze the lab-grown cells offers practical advantages for storage and transportation, making them more accessible for patients.
“Developing personalised, patient-specific blood stem cells will prevent these complications, address donor shortages and, alongside genome editing, help correct underlying causes of blood diseases,” he added. cells work together to maintain our health: red blood cells transport oxygen, white blood cells protect against disease, and platelets prevent bleeding. This study could help in understanding their complex interactions for human health.
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