World-first: Deep brain stimulation enables paralyzed patient to walk again

In this clinical trial, the participants received deep brain stimulation (DBS) in a region of the brain called the lateral hypothalamus (LH).

A ski accident left 54-year-old Wolfgang Jäger paralyzed in 2006. He has been confined to a wheelchair since sustaining a spinal cord injury.

In this clinical trial, the participants received deep brain stimulation in the surprising region of the brain called the lateral hypothalamus . DBS is a neurosurgical technique used to treat movement disorders like Parkinson’s disease. It involves implanting electrodes to modulate neural activity for motor control. The effects of DBS were both immediate and long-lasting. For instance, the treatment immediately improved walking ability during rehabilitation. Moreover, it resulted in sustained improvements in motor function.

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