Working Out a Little Harder Could Keep Your Brain a Lot Sharper

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Working Out a Little Harder Could Keep Your Brain a Lot Sharper
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Just a few moments of extra effort when hyou're working out could be helping your brain stay sharp for years to come, a new study suggests.

how exercise helps the brain, but some experts believe it has to do with the release of brain-protective molecules like cathepsin B and brain-derived neurotrophic factor .

“These two molecules have been shown to be potentially protective of cognitive health,” says study author Corey Mazo, a PhD student and researcher in the university’s Human Bioenergetics Laboratory. “Intensive bouts of exercise were the most effective at increasing circulating levels of CTSB and BDNF.

The study sheds light on how these rises might happen. Muscle biopsies taken before and after the high-intensity workout showed presence of CTSB and BDNF. They also revealed an increase in BDNF gene expression, which sets the stage for making BDNF. This suggests that muscle contractions may play a role in triggering the brain-boosting benefits.

The study builds on previous research linking exercise with brain benefits, the researchers say. Physically active adults have a nearly

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