Wireless molecular-electrical communications for tumor-cell-induced apoptosis

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Wireless molecular-electrical communications for tumor-cell-induced apoptosis
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Researchers utilize electricity generated by wireless-induced redox interactions at bio-nanoantennae to cause apoptosis in cancerous cells.

By Pooja Toshniwal PahariaSep 18 2023Reviewed by Benedette Cuffari, M.Sc. Quantum biological electron transfer is an important biological activity that is influenced by quantum mechanical factors such as electron tunneling . This mechanism, which includes cellular respiration and homeostasis, has diagnostic and therapeutic applications.

Study: Wireless Electrical-Molecular Quantum Signalling for Cancer Cell Induced Death. Image Credit: Edge Creative / Shutterstock.com For the experiments, 100 nm PEGylated spherical gold nanoparticles were utilized as bipolar nanoelectrodes to electrically connect with cells at the molecular level. Transmission electron microscopy , dynamic light scattering , Zeta potential, and ultraviolet-visible light characterization revealed that GNP100 was successfully bifunctionalized with r.Cyt c and Z.

Voltage and frequency were adjusted by analyzing the changes in metabolic activities of the cancer cells as the preliminary readout of Cyt c redox switching to test the electric input that may be detected by intracellular bio-nanoantennae for generating wireless electrochemistry. To investigate the mechanism of cell death, flow cytometry and confocal microscopy were used.

AC-EF triggered molecular actuation through bio-nanoantennae in the therapy of an illness, which indicates that it is a quantum-functional-type medical tool. This might facilitate the development of quantum nanopharmaceuticals and cancer therapies, as well as provide a cutting-edge method of controlling cell metabolism.

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