Pharmacist Mark Mikhael has lost 50 lb over the past 12 months. He no longer has diabetes and finds himself at his ideal body weight with his cholesterol below 200.
Pharmacist Mark Mikhael has lost 50 pounds over the past 12 months. He no longer has diabetes and finds himself"at my ideal body weight," with his cholesterol below 200 for the first time in 20 years."I feel fantastic," he said.
In recent years, the US healthcare system has come to depend on compounding pharmacies, many of which are run as nonprofits, to plug supply holes of crucial drugs like cancer medicines cisplatin, methotrexate, and 5-fluorouracil. The compounded forms are significantly cheaper than the branded drugs. Patients pay about $100-$450 a month, compared with list prices of roughly $1000-$1400 for Lilly and Novo Nordisk products.
In response, Congress and the FDA had strengthened oversight. Mikhael's company is an outsourcing facility, or 503B compounding pharmacy — so-named for a section of the 2013 law that set new requirements for drug compounders. The companies are licensed to make slightly different versions of FDA-approved drugs in response to shortages or a patient's special needs.
The compounders say the companies should increase production if they're worried about competition. Like the dozens of other drugs they produce for hospitals and medical practices, the compounders say, the two diet drugs are essential products. Compounders can buy powdered semaglutide from some US distributors for less than $4000 a gram, said Matthew Johnson, president and CEO of distributor Pharma Source Direct. That comes out to as little as $10 per weekly 2.5-microgram dose — not including overhead and other costs.
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