What to know about prescription drugs promising weightloss. Health
The $132 million deal with Sequence is the just the latest commercial push into the red-hot market for prescription drugs that promise significant weight loss. For months, the diabetes drug Ozempic has been touted on social media by celebrities -- even though it's not approved for weight loss. The demand for it sparked shortages.
Doctors prescribe the medications to people with diabetes alone, or to people who are obese or who are overweight with additional health problems. Most of these types of drugs are delivered through weekly injections. A newer drug, called tirzepatide, mimics the action of two hormones for even greater effect. The Eli Lilly and Co. drug, sold under the brand name Mounjaro, is now approved to treat diabetes, but the FDA granted fast-track status to review it to treat obesity. A decision is expected this spring.
A clinical trial of Mounjaro, which is still being studied, saw mean weight loss of 15% to 21% of body weight depending on the dose, compared with a weight loss of about 3% for people taking placebo, or dummy drug. "There is a real physical phenomenon," he said."There is a resistance mechanism that is a coordinated effort by the body to prevent you from losing weight."
What should people watch out for? These new medications could be an effective part of a multifaceted approach to weight loss, said Dr. Amy Rothberg, an University of Michigan endocrinologist who directs a virtual weight management and diabetes program called Rewind.
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