Ongoing efforts aim to differentiate biologically refractory cases from cases with comorbid conditions and social factors that can contribute to treatment nonresponse.
CLEVELAND — Despite an expanding arsenal of disease-modifying antirheumatic drugs , many patients with axial spondyloarthritis and psoriatic arthritis still struggle to reach remission even after trying multiple advanced treatments.
"Apart from the persistent articular and periarticular inflammation, there could be multiple noninflammatory factors that may be contributing to this treatment-resistant disease, including comorbid conditions such as obesity, cardiovascular disease, fibromyalgia, and even social factors such as limited access to medications," she told.
Treatment according to existing recommendations and failure of at least two different bDMARDs or tsDMARDs with different mechanisms "What should be ruled out in order to exclude so-called noninflammatory causes of pain?" he continued."It will require some Delphi exercises and consensus approach."
Axspa Psoriatic Arthritis Arthropathic Psoriasis Psoriatic Arthropathy Psa Rheumatoid Arthritis RA - Rheumatoid Arthritis Rheumatoid Arthritis (RA) Refractory Patient Care Management Ankylosing Spondylitis Rheumatoid Spondylitis Rheumatoid Arthritis Of The Spine Bechterew's Disease Bechterew Syndrome Marie Strumpell Disease Marie Struempell Disease
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