The obesity drugs lower blood sugar and slow down digestion, so people feel full longer.
They also affect signals in the brain linked to feelings of fullness and satisfaction, tamping down appetite, food-related thoughts and cravings.In a trial, adults who took Wegovy saw a weight loss of nearly 35 pounds, or about 15% of their body weight.The latest study of tirzepatide studied the drug in more than 900 patients with diabetes who were overweight or had obesity over nearly 17 months.
However, it appears that if people taking the drugs stop, they regain the weight they lost - and the health problems that came with it.In a typical weight-loss program where participants rely only on diet and exercise, research shows only about a third of people will lose 5% or more of their body weight, said Dr. Louis Aronne, director of the Comprehensive Weight Control Center at Weill Cornell Medicine.
There are several hormones that respond to reduced calorie intake by ramping up hunger to maintain body mass.The most common side effects are short-lived gastrointestinal issues such as nausea, vomiting, constipation, diarrhea and stomach pain.
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