What is mifepristone, the drug at the heart of the Texas medication abortion lawsuit?

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What is mifepristone, the drug at the heart of the Texas medication abortion lawsuit?
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A federal judge in Texas has said he will suspend the approval of mifepristone, a drug approved by the US Food and Drug Administration that has been shown to be safe and effective for more than two decades.

— that has been shown to be safe and effective for more than two decades, although he is pausing his ruling for seven days so the federal government can appeal.

Mifepristone is marketed under the brand names Mifeprex and Korlym, and it's sometimes known as RU 486.Mifepristone blocks a hormone called progesterone, which helps the body maintain the inside of the uterus so a pregnancy can continue. A healthy uterine lining is what supports a fertilized egg, embryo and fetus.Someone having a medication abortion takes mifepristone and then, after 24 to 48 hours, takes misoprostol.

Mifepristone's safety is on par with those of common over-the-counter pain relievers like ibuprofen and acetaminophen, studies show. Major adverse events like blood loss, hospitalization or a significant infection are"exceedingly rare," happening in less than 0.3% of patients, according to the medical associations' amicus brief.The mifepristone-misoprostol combination is the most common abortion method in the US.

Studies show that misoprostol alone is effective and safe for an abortion and is a"reasonable" option for people who want an abortion in the first trimester, according to a 2019 review of multiple studies, but the two-drug regimen is considered more effective.

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