Exactly how Americans will greet a COVID-19 vaccine is unknown, but polls have suggested many will be wary. In an Associated Press survey in late May, only half of respondents said they would get vaccinated.
"Because there was a rush to production, some people had safety concerns," Schoch-Spana said.
"When the first vaccine comes out, we will have some safety data from clinical trials," said Offit, who was not involved in the new report."But we won't have data on enough people to detect any rare side effects." He said it will be critical to communicate clearly about any vaccine's effectiveness and safety -- and its allocation.
Reaching out to minorities, particularly Black Americans, will be crucial. They have not only been hard-hit by the virus, Schoch-Spana said, but have long faced institutional racism in the health care system.
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