After a period of rapid market growth, cannabis use appears to be stabilizing while researchers learn more about the long-term health impacts and policy concerns.
More than 6 years after the legalization of nonmedical cannabis, Canadian scientists are reporting a mix of observations. Legalization has improved drug safety and reduced some health harms yet also raised questions about new high-strength products and consumer decision-making.from Statistics Canda, about a third of adults less than age 45 years have used cannabis during the past year. The rate of regular use seems to be much lower, however.
As cannabis research advances, Canadian scientists are studying various products on the market, health effects during pregnancy and adolescence, and long-term policy considerations.“Cannabis legalization in Canada led to an initial increase in the number of Canadians using cannabis, which has since levelled off.
As a result, Donnan and colleagues developed an education program called Drug Education Centered on Youth Decision Empowerment, which is based on harm reduction and prevention strategies linked to the opioid crisis in Canada. In preclinical models, Raha and colleagues look at compounds in cannabis — such as THC and cannabidiol — and changes to placental stem cells that are associated with cannabis use. So far, they’ve observed shifts in cellular bioenergetics, which could potentially affect fetal development, the release of certain hormones, and cardiac function. They’ve also observed changes in mammary glands and breast milk.
On the other hand, Laviolette’s lab is also investigating interventions and supplements — such as precognitive amino acids — that can reduce neuroinflammation and counteract some of the negative effects of THC.
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