Almost 12% of patients with CRC are readmitted within 31 days after surgery, with certain demographic, surgical, and tumor-related characteristics increasing the risk, a meta-analysis finds.
Almost 12% of patients with colorectal cancer had unplanned readmissions within 31 days after surgery. Multiple risk factors were identified, including older age, comorbidities, advanced tumor stage, postoperative complications , and tumor location in the rectum, whereas female sex emerged as a protective factor.
The high rate of unplanned readmissions within 31 days after CRC surgery poses a significant challenge and burden on patients and healthcare systems, but the identified risk factors for these readmissions vary across the literature. Researchers conducted systematic literature searches of eight databases up to January 2025 and performed a meta-analysis of 15 studies to investigate the incidence and risk factors for unplanned readmissions within 31 days after CRC surgery. They analyzed data of 693,917 patients with an endoscopic or pathologic diagnosis of CRC who underwent surgery, of whom 63,906 had unplanned readmissions. The overall quality of the included studies ranged from moderate to high, with the Newcastle-Ottawa Scale classifying 73% as high-quality.All 15 studies investigated the incidence of unplanned readmissions within 31 days following CRC surgery, yielding an overall rate of 11.73%. The risk factors associated with unplanned readmissions post-CRC surgery included older age , blood transfusion , postoperative complications and stoma creation (OR, 1.70;IN PRACTICE: “The occurrence of postoperative is the result of multiple contributing factors; therefore, healthcare providers need to systematically assess patient risks and develop targeted intervention strategies,” the authors wrote. “By establishing risk alert systems, optimizing perioperative management protocols, and implementing individualized interventions, the incidence of postoperative can be effectively reduced, thereby improving short-term outcomes and enhancing overall healthcare quality.”
Colorectal Cancer (CRC) Surgery Tumor Patient Safety Postoperative Complications Postoperative Complication Postoperative Meta-Analysis Rectum Blood Transfusion Social Determinants Of Health SDOH Social Determinants Of Health (SDOH) Artificial Intelligence Deep Learning AI NPL Machine Learning ML Natural Language Processing Artificial Neural Networks Blood Cancer
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