For the last three years, Cleveland Clinic researchers have been studying the possibility of repurposing a well-known drug called Sildenafil for Alzheimer’s disease.
For those unfamiliar, Sildenafil is normally used to treat individuals with erectile dysfunction or high blood pressure.
However, researchers have discovered that the drug could also be beneficial when it comes to preventing and possibly treating Alzheimer’s. According to Dr. Feixiong Cheng, who led the research, they looked at computational models, insurance claims data, and brain cells in Alzheimer’s patients. Based on what they found, Sildenafil appears to lower levels of certain proteins in the brain, which are linked to Alzheimer’s.Cheng said repurposing a drug that’s already on the market is much more affordable than creating a new one.
Cheng said it’s important to emphasize that while early research has been hopeful, people should not use this drug for Alzheimer’s prevention purposes.
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