Week 5 picks: Breaking down Oregon-Penn State, Alabama-Georgia and all the big games

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Week 5 picks: Breaking down Oregon-Penn State, Alabama-Georgia and all the big games
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Jon Wilner's Pac-12 Hotline is brought to KSL.com through a partnership with the Bay Area News Group.Jon Wilner has been covering college sports for decades and is an AP Top 25 football and basketball voter as well as a Heisman Trophy voter.

Welcome the Hotline's weekly picks against the point spread, published Thursdays throughout the regular season with a focus on the top games nationally and the most intriguing matchups across the West.

Last week, we were 6-4. Lines are courtesy of vegasinsider.com. Picks are for entertainment purposes only … unless they aren't.If there was ever a week to ignore the Hotline's picks, cast point spreads aside and simply enjoy the games, this is it.Week 5 of the 2025 season is unlike any week of any season we can remember.And yes, that includes rivalry weekends at the end of the season.It's fully loaded from start to finish, with ranked teams in perilous spots and epic, concurrent showdowns on NBC and ABC in the late afternoon broadcast window.There are four matchups of ranked teams, and that list doesn't include the nation's No. 1 team venturing to a hostile environment to face an undefeated opponent. Nor does it include Notre Dame on the road in the SEC.And let's make no mistake: Week 5 is a testament to the expanded, engorged Big Ten and SEC and their lineups of marquee programs.This is a week that justifies the massive dollars and awkward geography of realignment.Here are the top matchups by broadcast window: 9 a.m.: No. 21 USC at No. 23 Illinois and No. 22 Notre Dame at Arkansas 12:30 p.m.: No. 1 Ohio State at Washington , No. 4 LSU at No. 13 Mississippi , Auburn at No. 9 Texas A&M and No. 11 Indiana at Iowa 4:30 p.m.: No. 6 Oregon at No. 3 Penn State and No. 17 Alabama at No. 5 Georgia As you can see, the Big 12 is not involved. Its best game, TCU at Arizona State, is slotted for Friday evening, which is probably for the better — the matchup would get lost on Saturday. Nor is the ACC involved. Its top-ranked team, No. 2 Miami, is idle, and No. 8 Florida State plays Friday.No matter. This weekend marks the rare alignment of Big Ten and SEC schedules in which both conferences offered their TV partners showcase weekends.To the picks ... Season record: 20-20-1 Five-star special: 2-2 All times PacificTCU at Arizona State Kickoff: 6 p.m. on FoxComment: The Horned Frogs have been the more impressive team thus far — quarterback Josh Hoover has next-level arm talent — but Friday road assignments in conference play are daunting. ASU lost a close game at Mississippi State and won a close

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