Volunteers to be infected with Covid as part of new U.K. trial
The U.K. government announced Tuesday it is investing 33.6 million pounds in the first stage of what are known as"challenge trials."a potential vaccineFirst, scientists need to artificially manufacture the virus and work out the smallest dose that will infect volunteers, all healthy adults between ages 18 and 30.If that stage passes regulatory and ethical approval, the challenge trials themselves would take place between January and March next year, the U.K.
After the first stage is complete, the company will submit its proposal for how the trials should work to the government's medical and ethical regulators for approval in November, according to Dr. Martin Johnson, chief medical officer at hVIVO. , where large numbers of people — as many as tens of thousands — are given the vaccine, while others get a placebo.
A challenge trial could shorten the timeline: All volunteers get the vaccine, and all of them get the virus too. Researchers say a group of just 40 volunteers would likely tell them a huge amount about any vaccine candidate in just a short space of time. Everyone accepts there are risks.
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