Vaccine Targeting Fast-Spreading Omicron Subvariants Could Be Ready For Fall As Pfizer, BioNTech Announce Trials

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Vaccine Targeting Fast-Spreading Omicron Subvariants Could Be Ready For Fall As Pfizer, BioNTech Announce Trials
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Pfizer and BioNTech will begin trials of their updated mRNA Covid-19 vaccine designed to protect against the newer BA.4 and BA.5 sub-variants of the coronavirus later this month.

for the second quarter of 2022, where the German vaccine maker reported a total revenue of €3.2 billion —lower than analyst estimates.

BioNTech and its American partner Pfizer have started manufacturing “bivalent” Omicron BA.1 and BA.4/BA.5 vaccines that will offer protections both against the fast spreading newer variants and earlier variants, the company said. The company claims it will be able roll out the updated shots by October—in time for potential fall boosters—if it receives regulatory approval.

Pfizer and BioNTech have already carried out clinical trials for their BA.1 Omicron-focussed vaccine—it was shown to produce higher neutralizing antibodies against the variant—and have submitted the findings to regulators.submit updated clinical trial data for the BA.4/BA.5 adapted shots. The agency will instead approve the modified vaccines using clinical data from the BA.1 vaccine trials. This will allow the updated vaccines to be approved quicker.

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