SPONSORED: Bone marrow cancer research has taken a step forward thanks to a new drug studied at the Mays Cancer Center at UT Health San Antonio.
Dr. Ruben Mesa, FACP, collaborates with physicians and scientists to unlock the mysteries of cancer and translate research into life-saving treatments. His recent findings point to a new drug to treat myelofibrosis .Ruben Mesa, MD, FACP, executive director of the Mays Cancer Center at UT Health San Antonio, has seen too many patients and families struggle with deadly bone marrow cancers.
He has been principal investigator or co-principal investigator of more than 70 clinical trials that have resulted in MPN drug therapies, several of which have gained U.S. Food and Drug Administration approval. Whoops! There was an error and we couldn't process your subscription. Please reload the page and try again.
Momelotinib, however, is the first drug that inhibits both JAK and ACVR1, Mesa said. “It has JAK1, JAK2 and ACVR1 inhibitors combined in one drug and addresses chronic inflammation due to the hyperactivation of ACVR1 as a consequence of the disease.”Of the enrolled participants, 130 received momelotinib and 65 got danazol. Participants did not know until after 24 weeks which drug they received, and those in the danazol group were allowed to cross over to momelotinib at that time.
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