Osteoporosis is a rising public health issue. Despite significant therapeutic progress, there is a healthcare gap for individuals with a high risk of fracture. How can nanoscience help?
By Arzoo PuriFeb 6 2023Reviewed by Megan Craig, M.Sc. Osteoporosis is a rising public health issue. Despite significant therapeutic progress, there is a healthcare gap for individuals with a high risk of fracture. This article focuses on how nanoscience can be used to treat osteoporosis.
The development of the disease is indicated by hip or bone mineral density measurements that are two and a half standard deviations or lower than the mean for healthy individuals. What are the Challenges Faced During Treatment? Despite these significant advances in treatment, many patients who would benefit from pharmacological therapy refuse to take anti-resorptive medications, particularly bisphosphonates. This is due to concerns about uncommon side effects and a lack of credible evidence supporting their long-term efficacy.
How Can Nanoscience Help to Treat Osteoporosis? One of the novel strategies to improve osteoporosis treatment is the development of nanomaterial-based drug delivery systems that target the bone. These nano-drug systems reduce systemic toxicity and enhance the therapeutic efficacy and pharmacokinetic profile of therapeutic agents.
Graphene eBook Compilation of the top interviews, articles, and news in the last year. Download a free copy Image Credit: Lilia Solonari/Shutterstock.com The benefit of ultrasonic-responsive nanobubbles is that they serve as a dual-acting technology, in which ultrasound is used to disrupt bubbles, gene delivery, and even help bone development.
Dr. Kassim Javaid from The University of Oxford quoted, "we ran a pilot with Nanox.Al's vertebral compression fracture algorithm with the purpose of evaluating how Al based technology can help increase patient flow into Oxford's Fracture Liaison Service . The pilot was successful, as accuracy was above 90%."
Continue reading: Characterizing Nanocomposites in Bones with the Use of X-Ray Diffraction References and Further Reading Osteoporosis Overview | NIH Osteoporosis and Related Bone Diseases National Resource Center. . Retrieved January 24, 2023, from https://www.bones.nih.gov/health-info/bone/osteoporosis/overview
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