A small molecule drug that can target the brain’s circadian clock proteins may prove effective for treating glioblastoma, the most common cancerous brain tumor, say Keck School of Medicine do…
LOS ANGELES — The identification of a small molecule drug that can target the brain’s circadian clock proteins may prove effective for treating glioblastoma, the most common cancerous brain tumor in adults, researchers at the Keck School of Medicine of USC announced Monday.
The discovery has led to a potential breakthrough: the identification of a small molecule drug, known as SHP656, that can target the clock proteins and may prove effective for treating the disease, according to USC.Biological Sciences at the Keck School of Medicine and director of the USC Michelson Center for Convergent Bioscience.
The first symptoms of glioblastoma can include everything from blurred vision, headaches and nausea to seizures and personality changes. Patients typically undergo a brain scan, which identifies the tumor, then receive a combination of surgery, radiation and chemotherapy treatment. While most tumors shrink substantially after the initial treatment, few patients experience sustained remission.
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