Week 6 features two of the most savory matchups of the 2022 NFL season. Our USA TODAY Sports NFL experts make their predictions for every game, including Sunday's huge showdown between the Buffalo Bills and Kansas City Chiefs:
Lorenzo Reyes is back with his picks heading into Week 6, including his choice for the highly anticipated Bills-Chiefs matchup.Week 6 of the NFL season comes bearing gifts – serving up two of the most savory matchups of a still-young 2022 season.
Sunday afternoon, the Buffalo Bills and Kansas City Chiefs will meet for the fifth time in two years. The Bills cruised 38-20 in last year's regular-season contest at Arrowhead Stadium, but it remains the only time Josh Allen has beaten Patrick Mahomes. Buffalo is favored Sunday, but the real test likely won't come until January – when the Bills have fallen at K.C. the last two postseasons.
Sunday night, the Dallas Cowboys get a shot at dealing the Philadelphia Eagles their first loss of the 2022 season. A Dallas win would also mean a first-place tie atop the NFC East. A Philly victory would give the Iggles their first 6-0 start since the 2004 team advanced to Super Bowl 39.
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