Literally...stop trying the Benadryl challenge.
, it can come with side effects, which become more serious as the dose increases. And the dosage that can cause hallucinations is high enough to cause other serious issues, including potentially lethal effects on the heart.
But, paradoxically, it can cause agitation, confusion, increased body temperature, hallucinations, and even seizures at higher doses, Dr. Stolbach says, noting that it would take upwards of a dozen pills to see these effects in an adult. Many of these adverse effects are due to the fact that diphenhydramine is not just an antihistamine, Dr. Stolbach explains. It also inhibits the effects of the neurotransmitter acetylcholine, which is involved in regulating blood vessel dilation, muscle contractions, and your heart rate.
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