Do your genes look the same if you look the same?
A person's unrelated lookalike, commonly known as a doppelganger, may actually share genes that affect not only how they appear, but also their behavior.
“Our study provides a rare insight into human likeness by showing that people with extreme lookalike faces share common genotypes, whereas they are discordant at the epigenome and microbiome levels,” said senior study author Manel Esteller, of the Josep Carreras Leukaemia Research Institute in Barcelona.
“This unique set of samples has allowed us to study how genomics, epigenomics and microbiomics can contribute to human resemblance,” Esteller said. For half of the lookalike pairs, all three algorithms clustered them together. Genetic analysis found that nine of these 16 pairs clustered together based on 19,277 common single-nucleotide polymorphisms.
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